| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (2) |  | A Fish Called Wanda (1988) | £718,594 | £1,006,032 | £2,024,732 | -29% | 2 |
| 2 (1) |  | Buster (1988) | £717,977 | £969,269 | £2,753,364 | -31% | 6 |
| 3 (new) |  | Big (1988) | £716,688 | £716,688 | £716,688 | new | 1 |
| 4 (3) |  | Good Morning Vietnam (1988) | £283,989 | £397,585 | £2,990,925 | -50% | 4 |
| 5 (4) |  | Midnight Run (1988) | £112,844 | £157,982 | £1,229,999 | -60% | 3 |
| 6 (5) |  | The Running Man (1988) | £45,829 | £61,869 | £1,432,987 | -47% | 5 |
| 7 (6) |  | Distant Voices, Still Lives (1988) | £29,714 | £41,600 | £536,029 | -50% | 4 |
| 8 (8) |  | Big Business (1988) | £11,213 | £15,698 | £987,646 | -37% | 8 |
| 9 (9) |  | Beetlejuice (1988) | £10,451 | £15,154 | £2,345,200 | -29% | 10 |
| 10 (10) |  | Coming to America (1988) | £8,712 | £11,761 | £3,470,360 | -20% | 12 |
| 11 (11) |  | Rambo III (1988) | £3,269 | £4,577 | £1,655,612 | -55% | 9 |
| 12 (12) |  | The Last Temptation of Christ (1988) | £1,089 | £1,525 | £326,268 | -63% | 7 |