| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Kevin and Perry Go Large (2000) | £2,404,517 | £2,404,517 | £2,404,517 | new | 1 |
| 2 (1) |  | Pokémon: The First Movie (2000) | £1,257,082 | £3,774,023 | £6,607,744 | -56% | 2 |
| 3 (2) |  | Erin Brockovich (2000) | £1,137,153 | £2,217,079 | £6,368,617 | -23% | 3 |
| 4 (4) |  | The Tigger Movie (2000) | £826,144 | £1,846,846 | £2,528,125 | 30% | 2 |
| 5 (new) |  | American Psycho (2000) | £749,526 | £749,526 | £749,526 | new | 1 |
| 6 (3) |  | Mission to Mars (2000) | £368,600 | £863,413 | £1,630,897 | -52% | 2 |
| 7 (5) |  | American Beauty (1999) | £324,988 | £670,434 | £20,484,103 | -39% | 13 |
| 8 (new) |  | The Story of Us (2000) | £231,564 | £231,564 | £231,564 | new | 1 |
| 9 (6) |  | Lake Placid (2000) | £175,584 | £461,614 | £3,244,303 | -61% | 4 |
| 10 (8) |  | Toy Story 2 (1999) | £164,235 | £418,416 | £42,970,894 | -19% | 11 |
| 11 (new) |  | Snow Day (2000) | £99,641 | £99,641 | £99,641 | new | 1 |
| 12 (7) |  | Love, Honor and Obey (2000) | £89,251 | £243,371 | £1,040,322 | -68% | 3 |
| 13 (re) |  | Boys Don't Cry (2000) | £79,576 | £79,576 | £254,731 | RE | 1 |
| 14 (13) |  | Being John Malkovich (2000) | £72,292 | £157,292 | £1,702,922 | -35% | 6 |
| 15 (9) |  | The Green Mile (2000) | £65,192 | £187,737 | £6,688,317 | -65% | 9 |