| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Snatch (2000) | £3,180,002 | £3,180,002 | £3,180,002 | new | 1 |
| 2 (1) |  | X-Men (2000) | £1,196,233 | £2,784,668 | £12,046,637 | -41% | 3 |
| 3 (3) |  | Stuart Little (2000) | £498,389 | £1,134,436 | £15,988,620 | -9% | 10 |
| 4 (4) |  | Chicken Run (2000) | £486,327 | £1,067,450 | £27,382,773 | -9% | 10 |
| 5 (2) |  | Shanghai Noon (2000) | £414,934 | £958,463 | £1,704,594 | -44% | 2 |
| 6 (5) |  | Gone In 60 Seconds (2000) | £294,004 | £693,629 | £7,005,680 | -42% | 5 |
| 7 (6) |  | The Perfect Storm (2000) | £189,045 | £443,365 | £8,645,916 | -41% | 6 |
| 8 (7) |  | Cherry Falls (2000) | £184,874 | £386,018 | £627,189 | -23% | 2 |
| 9 (8) |  | Gossip (2000) | £177,401 | £392,523 | £600,225 | -15% | 2 |
| 10 (9) |  | High Fidelity (2000) | £109,914 | £255,239 | £4,557,868 | -43% | 7 |
| 11 (11) |  | Gladiator (2000) | £97,453 | £197,882 | £30,510,498 | -21% | 17 |
| 12 (15) |  | The Flintstones In Viva Rock Vegas (2000) | £94,731 | £203,850 | £1,790,493 | -1% | 6 |
| 13 (new) |  | Nurse Betty (2000) | £69,723 | £69,723 | £69,723 | new | 1 |
| 14 (10) |  | Mission:Impossible 2 (2000) | £64,998 | £279,979 | £17,291,606 | -52% | 9 |
| 15 (12) |  | Final Destination (2000) | £64,721 | £156,251 | £10,218,118 | -41% | 15 |