| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (2) |  | What Lies Beneath (2000) | £1,341,518 | £2,291,676 | £7,681,728 | -21% | 3 |
| 2 (1) |  | Dinosaur (2000) | £820,419 | £1,374,678 | £11,567,893 | -62% | 4 |
| 3 (4) |  | Billy Elliot (2000) | £751,293 | £1,369,044 | £12,796,352 | -28% | 6 |
| 4 (6) |  | Road Trip (2000) | £544,431 | £950,484 | £6,506,939 | -28% | 4 |
| 5 (3) |  | Book of Shadows: Blair Witch 2 (2000) | £423,877 | £971,404 | £2,065,821 | -61% | 2 |
| 6 (5) |  | The Little Vampire (2000) | £390,226 | £680,612 | £3,113,795 | -51% | 4 |
| 7 (7) |  | Coyote Ugly (2000) | £387,437 | £701,265 | £1,883,249 | -17% | 3 |
| 8 (new) |  | Purely Belter (2000) | £289,571 | £289,571 | £289,571 | new | 1 |
| 9 (new) |  | Wonder Boys (2000) | £260,126 | £260,126 | £260,126 | new | 1 |
| 10 (new) |  | Loser (2000) | £173,016 | £173,016 | £173,016 | new | 1 |
| 11 (9) |  | Mohabbatein (2000) | £158,193 | £249,925 | £496,293 | -36% | 2 |
| 12 (10) |  | Bring It On (2000) | £138,636 | £211,915 | £1,041,982 | -42% | 3 |
| 13 (8) |  | Nutty Professor II: The Klumps (2000) | £116,618 | £226,888 | £5,104,146 | -65% | 5 |
| 14 (13) |  | Memento (2000) | £100,376 | £175,890 | £449,120 | -17% | 3 |
| 15 (11) |  | Hollow Man (2000) | £94,157 | £178,445 | £5,968,350 | -47% | 6 |