| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Meet the Parents (2000) | £2,261,785 | £2,261,785 | £2,261,785 | new | 1 |
| 2 (1) |  | How the Grinch Stole Christmas (2000) | £1,614,860 | £2,272,585 | £8,757,293 | -37% | 3 |
| 3 (3) |  | 102 Dalmatians (2000) | £956,729 | £1,286,960 | £2,466,718 | -19% | 2 |
| 4 (2) |  | Charlie's Angels (2000) | £647,461 | £1,217,913 | £10,429,143 | -52% | 4 |
| 5 (new) |  | The 6th Day (2000) | £586,401 | £586,401 | £586,401 | new | 1 |
| 6 (4) |  | What Lies Beneath (2000) | £124,051 | £262,348 | £12,938,613 | -58% | 9 |
| 7 (8) |  | Billy Elliot (2000) | £51,171 | £148,538 | £16,557,388 | -63% | 12 |
| 8 (9) |  | Small Time Crooks (2000) | £48,928 | £107,994 | £504,966 | -59% | 3 |
| 9 (10) |  | Coyote Ugly (2000) | £42,910 | £99,510 | £3,584,855 | -63% | 9 |
| 10 (6) |  | The Art of War (2000) | £41,195 | £124,505 | £290,335 | -75% | 2 |
| 11 (7) |  | Urban Legends: Final Cut (2000) | £39,056 | £117,723 | £665,544 | -76% | 3 |
| 12 (13) |  | Memento (2000) | £25,658 | £57,182 | £1,149,376 | -51% | 9 |
| 13 (5) |  | Red Planet (2000) | £21,699 | £103,787 | £755,489 | -88% | 3 |
| 14 (11) |  | Bedazzled (2000) | £15,005 | £36,475 | £3,246,955 | -81% | 6 |
| 15 (re) |  | Mohabbatein (2000) | £14,964 | £14,964 | £928,921 | RE | 3 |