| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Pirates of the Caribbean: Dead Man's Chest (2006) | £13,740,784 | £13,740,784 | £13,740,784 | new | 1 |
| 2 (1) |  | Over the Hedge (2006) | £2,167,916 | £3,364,470 | £6,953,508 | -40% | 2 |
| 3 (2) |  | Just My Luck (2006) | £424,436 | £790,766 | £1,370,072 | -27% | 2 |
| 4 (3) |  | The Fast and the Furious: Tokyo Drift (2006) | £332,089 | £634,184 | £5,293,481 | -38% | 4 |
| 5 (5) |  | The Wind That Shakes the Barley (2006) | £269,144 | £573,446 | £1,737,715 | -20% | 3 |
| 6 (4) |  | The Lake House (2006) | £247,884 | £584,499 | £2,371,554 | -38% | 3 |
| 7 (6) |  | The Da Vinci Code (2006) | £121,850 | £322,919 | £29,954,179 | -47% | 8 |
| 8 (new) |  | District B13 (2006) | £98,747 | £98,747 | £98,747 | new | 1 |
| 9 (7) |  | X-Men: The Last Stand (2006) | £87,582 | £231,292 | £18,973,585 | -62% | 7 |
| 10 (12) |  | Krrish (2006) | £60,344 | £119,652 | £551,916 | -46% | 3 |
| 11 (8) |  | Fearless (2006) | £54,492 | £183,553 | £1,032,193 | -72% | 3 |
| 12 (13) |  | Thank You For Smoking (2006) | £48,135 | £123,957 | £847,850 | -46% | 4 |
| 13 (9) |  | Hard Candy (2006) | £36,008 | £136,625 | £1,728,022 | -74% | 4 |
| 14 (new) | | Heading South (2006) | £35,787 | £35,787 | £35,787 | new | 1 |
| 15 (11) | | Reeker (2006) | £33,030 | £121,612 | £233,659 | -71% | 2 |