| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Cars (2006) | £2,668,968 | £2,668,968 | £2,668,968 | new | 1 |
| 2 (1) |  | Pirates of the Caribbean: Dead Man's Chest (2006) | £2,625,103 | £5,549,415 | £39,281,915 | -32% | 4 |
| 3 (2) |  | The Break Up (2006) | £1,414,268 | £3,054,973 | £5,467,070 | -41% | 2 |
| 4 (3) |  | Superman Returns (2006) | £1,345,200 | £2,934,078 | £11,989,893 | -42% | 3 |
| 5 (4) |  | Stormbreaker (2006) | £780,255 | £1,886,832 | £3,131,724 | -37% | 2 |
| 6 (5) |  | Garfield 2 (2006) | £562,057 | £1,329,345 | £2,068,905 | -24% | 2 |
| 7 (6) |  | Over the Hedge (2006) | £361,910 | £1,029,164 | £10,882,762 | -39% | 5 |
| 8 (new) |  | Stay Alive (2006) | £140,126 | £140,126 | £140,126 | new | 1 |
| 9 (7) |  | The Wind That Shakes the Barley (2006) | £131,351 | £278,793 | £2,773,645 | -15% | 6 |
| 10 (new) |  | Omkara (2006) | £91,294 | £91,294 | £91,294 | new | 1 |
| 11 (new) |  | Angel A (2005) | £47,825 | £47,825 | £47,825 | new | 1 |
| 12 (new) |  | Warrior King (2005) | £34,295 | £34,295 | £34,295 | new | 1 |
| 13 (8) |  | Little Fish (2005) | £28,640 | £61,596 | £112,829 | -44% | 2 |
| 14 (14) |  | Thank You For Smoking (2006) | £17,844 | £40,596 | £1,019,728 | -27% | 7 |
| 15 (15) |  | Deep Sea 3D (2006) | £17,197 | £36,869 | £519,838 | 10% | 12 |
| 16 (new) |  | Renaissance (2006) | £14,623 | £14,623 | £14,623 | new | 1 |
| 17 (16) |  | Pretty Persuasion (2005) | £1,350 | £1,761 | £59,920 | 67% | 5 |