| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Night At the Museum (2006) | £7,690,312 | £7,690,312 | £7,690,312 | new | 1 |
| 2 (1) |  | Happy Feet (2006) | £1,818,714 | £3,317,661 | £13,862,684 | -11% | 4 |
| 3 (3) |  | Casino Royale (2006) | £1,417,179 | £2,767,305 | £49,641,433 | 29% | 7 |
| 4 (2) |  | The Holiday (2006) | £888,578 | £1,749,479 | £10,226,830 | -16% | 4 |
| 5 (new) |  | It's a Boy Girl Thing (2006) | £850,290 | £850,290 | £850,290 | new | 1 |
| 6 (6) |  | Flushed Away (2006) | £702,520 | £1,186,467 | £8,535,177 | -14% | 5 |
| 7 (5) |  | Eragon (2006) | £630,821 | £1,207,666 | £4,236,858 | -25% | 3 |
| 8 (7) |  | Déjà Vu (2006) | £602,214 | £1,191,377 | £3,544,518 | 8% | 3 |
| 9 (new) |  | Perfume: The Story of a Murderer (2006) | £485,200 | £485,200 | £485,200 | new | 1 |
| 10 (12) |  | Flags of Our Fathers (2006) | £145,758 | £268,957 | £366,722 | 33% | 2 |
| 11 (4) |  | The Santa Clause 3: The Escape Clause (2006) | £122,667 | £249,268 | £6,115,896 | -87% | 6 |
| 12 (11) |  | Bhagam Bhag (2006) | £81,828 | £216,946 | £347,071 | -37% | 2 |
| 13 (8) |  | Grounded: Unaccompanied Minors (2006) | £80,816 | £163,567 | £843,859 | -69% | 3 |
| 14 (13) |  | Pans Labyrinth (2006) | £78,904 | £144,292 | £1,682,180 | 9% | 6 |
| 15 (10) |  | Black Christmas (2006) | £53,986 | £132,547 | £1,001,618 | -75% | 3 |