| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Indiana Jones and the Kingdom of the Crystal Skull (2008) | £12,227,799 | £12,227,799 | £12,227,799 | new | 1 |
| 2 (2) |  | What Happens In Vegas... (2008) | £921,516 | £1,529,709 | £5,041,971 | -39% | 3 |
| 3 (1) |  | Iron Man (2008) | £834,863 | £1,420,101 | £14,416,787 | -56% | 4 |
| 4 (3) |  | Forgetting Sarah Marshall (2008) | £323,835 | £564,800 | £7,016,203 | -43% | 5 |
| 5 (4) |  | Nims Island (2008) | £294,201 | £351,701 | £2,481,509 | -35% | 4 |
| 6 (5) |  | Speed Racer (2008) | £162,399 | £235,129 | £1,129,067 | -60% | 3 |
| 7 (6) |  | Made of Honor (2008) | £120,576 | £254,061 | £2,198,818 | -58% | 4 |
| 8 (7) |  | Doomsday (2008) | £79,501 | £187,919 | £944,521 | -69% | 3 |
| 9 (9) |  | Caramel (2008) | £70,570 | £126,573 | £249,363 | -43% | 2 |
| 10 (8) |  | In Bruges (2008) | £60,185 | £114,390 | £4,648,307 | -55% | 11 |
| 11 (new) |  | Cassandras Dream (2008) | £47,359 | £47,359 | £47,359 | new | 1 |
| 12 (re) |  | Persepolis (2008) | £40,677 | £40,677 | £705,853 | RE | 4 |
| 13 (14) |  | Shutter (2008) | £33,742 | £75,286 | £147,860 | -54% | 2 |
| 14 (re) |  | The Spiderwick Chronicles (2008) | £30,194 | £30,194 | £10,530,519 | RE | 8 |
| 15 (16) | | Jannat (2008) | £29,895 | £55,232 | £104,487 | -39% | 2 |