| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Yes Man (2008) | £2,331,490 | £2,331,490 | £2,331,490 | new | 1 |
| 2 (new) |  | Bedtime Stories (2008) | £1,551,605 | £1,551,605 | £1,551,605 | new | 1 |
| 3 (new) |  | Australia (2008) | £1,294,414 | £1,294,414 | £1,294,414 | new | 1 |
| 4 (2) |  | Madagascar Escape 2 Africa (2008) | £1,188,113 | £3,170,266 | £16,042,979 | -36% | 4 |
| 5 (1) |  | Twilight (2008) | £1,153,607 | £2,430,254 | £4,938,676 | -54% | 2 |
| 6 (4) |  | The Day the Earth Stood Still (2008) | £521,000 | £1,079,944 | £5,914,271 | -48% | 3 |
| 7 (new) |  | Ghajini (2008) | £318,538 | £318,538 | £318,538 | new | 1 |
| 8 (6) |  | Inkheart (2008) | £310,374 | £1,008,455 | £2,635,649 | -44% | 3 |
| 9 (3) |  | Four Christmases (2008) | £275,693 | £1,314,645 | £9,832,403 | -74% | 5 |
| 10 (5) |  | The Tale of Despereaux (2008) | £240,043 | £721,618 | £1,282,488 | -57% | 2 |
| 11 (9) |  | Quantum of Solace (2008) | £192,126 | £373,892 | £50,405,045 | -6% | 9 |
| 12 (7) |  | Rab Ne Bana Di Jodi (2008) | £167,392 | £337,403 | £1,213,641 | -35% | 3 |
| 13 (8) |  | Changeling (2008) | £142,253 | £273,649 | £4,353,026 | -35% | 5 |
| 14 (10) |  | Transporter 3 (2008) | £75,972 | £189,325 | £2,446,717 | -56% | 4 |
| 15 (11) |  | A Bunch of Amateurs (2008) | £29,718 | £110,693 | £201,849 | -67% | 2 |