| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar (2009) | £5,527,039 | £8,382,719 | £49,374,516 | 14% | 5 |
| 2 (2) |  | Sherlock Holmes (2009) | £2,028,282 | £3,152,568 | £18,829,133 | 0% | 4 |
| 3 (4) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £1,542,970 | £1,856,076 | £16,862,702 | 21% | 4 |
| 4 (5) |  | Its Complicated (2009) | £1,300,580 | £2,192,598 | £3,291,257 | 16% | 2 |
| 5 (new) |  | Up In the Air (2009) | £1,298,023 | £1,298,023 | £1,298,023 | new | 1 |
| 6 (new) |  | The Book of Eli (2010) | £1,232,001 | £1,232,001 | £1,232,001 | new | 1 |
| 7 (3) |  | Daybreakers (2009) | £804,762 | £1,392,787 | £2,737,375 | -40% | 2 |
| 8 (6) |  | The Road (2010) | £470,652 | £882,828 | £1,509,975 | -25% | 2 |
| 9 (7) |  | Did You Hear About the Morgans? (2010) | £396,106 | £718,861 | £2,966,211 | -29% | 3 |
| 10 (9) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £282,047 | £363,743 | £6,545,874 | -4% | 5 |
| 11 (new) |  | All About Steve (2010) | £275,083 | £275,083 | £275,083 | new | 1 |
| 12 (new) |  | 44 Inch Chest (2010) | £152,171 | £152,171 | £152,171 | new | 1 |
| 13 (8) |  | Nine (2009) | £149,594 | £409,128 | £2,811,110 | -56% | 5 |
| 14 (10) |  | Sex & Drugs & Rock & Roll (2010) | £133,773 | £254,125 | £427,956 | -23% | 2 |
| 15 (11) |  | 3 Idiots (2009) | £119,450 | £186,532 | £1,556,346 | -15% | 4 |