| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar (2009) | £4,338,774 | £6,865,793 | £71,936,392 | -11% | 8 |
| 2 (new) |  | The Princess and the Frog (2010) | £2,239,759 | £2,224,108 | £2,239,759 | 99% | 2 |
| 3 (new) |  | Astro Boy (2009) | £1,091,872 | £1,091,872 | £1,091,872 | new | 1 |
| 4 (new) |  | Invictus (2009) | £1,068,388 | £1,068,388 | £1,068,388 | new | 1 |
| 5 (4) |  | Sherlock Holmes (2009) | £783,681 | £1,296,296 | £24,474,393 | -32% | 7 |
| 6 (3) |  | Edge of Darkness (2010) | £768,013 | £1,478,351 | £2,651,278 | -35% | 2 |
| 7 (new) |  | Youth In Revolt (2010) | £743,932 | £743,932 | £743,932 | new | 1 |
| 8 (2) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £729,683 | £883,837 | £20,837,031 | -39% | 7 |
| 9 (5) |  | Its Complicated (2009) | £560,573 | £1,195,627 | £8,288,948 | -34% | 5 |
| 10 (6) |  | Up In the Air (2009) | £481,810 | £945,658 | £5,580,729 | -34% | 4 |
| 11 (9) |  | Precious: Based On the Novel Push By Sapphire (2009) | £369,295 | £551,870 | £812,791 | 29% | 2 |
| 12 (8) |  | The Book of Eli (2010) | £225,850 | £495,781 | £4,017,681 | -53% | 4 |
| 13 (12) | | A Prophet (2010) | £126,606 | £270,983 | £960,306 | -38% | 3 |
| 14 (10) |  | Daybreakers (2009) | £84,483 | £221,057 | £4,185,646 | -65% | 5 |
| 15 (11) |  | Brother's (2010) | £83,156 | £232,589 | £1,028,334 | -60% | 3 |