| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar (2009) | £2,260,319 | £3,534,168 | £86,799,652 | -20% | 11 |
| 2 (3) |  | The Lovely Bones (2009) | £1,203,251 | £2,210,995 | £3,848,574 | -27% | 2 |
| 3 (new) |  | The Crazies (2010) | £1,194,207 | £1,194,207 | £1,194,207 | new | 1 |
| 4 (2) |  | The Princess and the Frog (2010) | £870,953 | £1,112,162 | £9,985,495 | -50% | 5 |
| 5 (5) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £853,859 | £1,187,942 | £6,413,038 | -43% | 3 |
| 6 (4) |  | Valentine's Day (2010) | £822,366 | £1,553,007 | £9,330,161 | -48% | 3 |
| 7 (new) |  | Leap Year (2010) | £728,251 | £728,251 | £728,251 | new | 1 |
| 8 (new) |  | From Paris With Love (2010) | £678,950 | £678,950 | £678,950 | new | 1 |
| 9 (12) |  | A Single Man (2010) | £381,489 | £683,169 | £1,950,350 | 1% | 3 |
| 10 (9) |  | Invictus (2009) | £292,899 | £569,718 | £4,225,080 | -49% | 4 |
| 11 (8) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £278,649 | £327,223 | £23,492,082 | -54% | 10 |
| 12 (10) |  | Astro Boy (2009) | £238,845 | £275,760 | £3,378,087 | -54% | 4 |
| 13 (6) |  | The Wolfman (2010) | £238,413 | £627,576 | £4,799,454 | -69% | 3 |
| 14 (7) |  | Solomon Kane (2009) | £215,632 | £522,678 | £1,134,564 | -65% | 2 |
| 15 (11) |  | My Name Is Khan (2010) | £185,330 | £356,044 | £2,316,393 | -59% | 3 |