| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Avatar (2009) | £2,260,319 | £3,534,168 | £86,799,652 | -20% | 11 |
| 2 (3) |  | The Lovely Bones (2009) | £1,203,251 | £2,210,995 | £3,848,574 | -27% | 2 |
| 3 (new) |  | The Crazies (2010) | £1,194,207 | £1,194,207 | £1,194,207 | new | 1 |
| 4 (2) |  | The Princess and the Frog (2010) | £870,953 | £1,112,162 | £9,985,495 | -50% | 5 |
| 5 (5) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £853,859 | £1,187,942 | £6,413,038 | -43% | 3 |
| 6 (4) |  | Valentine's Day (2010) | £822,366 | £1,553,007 | £9,330,161 | -48% | 3 |
| 7 (new) |  | Leap Year (2010) | £728,251 | £728,251 | £728,251 | new | 1 |
| 8 (new) |  | From Paris With Love (2010) | £678,950 | £678,950 | £678,950 | new | 1 |
| 9 (12) |  | A Single Man (2010) | £381,489 | £683,169 | £1,950,350 | 1% | 3 |
| 10 (9) |  | Invictus (2009) | £292,899 | £569,718 | £4,225,080 | -49% | 4 |
| 11 (8) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £278,649 | £327,223 | £23,492,082 | -54% | 10 |
| 12 (10) |  | Astro Boy (2009) | £238,845 | £275,760 | £3,378,087 | -54% | 4 |
| 13 (6) |  | The Wolfman (2010) | £238,413 | £627,576 | £4,799,454 | -69% | 3 |
| 14 (7) |  | Solomon Kane (2009) | £215,632 | £522,678 | £1,134,564 | -65% | 2 |
| 15 (11) |  | My Name Is Khan (2010) | £185,330 | £356,044 | £2,316,393 | -59% | 3 |
| 16 (new) | | Micmacs (2009) | £182,529 | £182,529 | £182,529 | new | 1 |
| 17 (new) |  | Extraordinary Measures (2010) | £131,759 | £131,759 | £131,759 | new | 1 |
| 18 (new) |  | Everybody's Fine (2009) | £68,948 | £68,948 | £68,948 | new | 1 |
| 19 (new) |  | Karthik Calling Karthik (2010) | £62,903 | £62,903 | £62,903 | new | 1 |
| 20 (re) |  | An Education (2009) | £38,480 | £38,480 | £2,318,901 | RE | 16 |
| 21 (new) | | Capitalism: A Love Story (2009) | £29,595 | £29,595 | £29,595 | new | 1 |
| 22 (re) |  | Planet 51 (2009) | £19,357 | £19,357 | £4,925,762 | RE | 12 |
| 23 (new) | | Teen Patti (2010) | £15,368 | £15,368 | £15,368 | new | 1 |
| 24 (new) | | Vinnaithaandi Varuvaayaa (2010) | £13,247 | £13,247 | £13,247 | new | 1 |
| 25 (re) |  | Sex & Drugs & Rock & Roll (2010) | £8,202 | £8,202 | £841,328 | RE | 7 |
| 26 (re) |  | Nine (2009) | £5,541 | £5,541 | £3,244,571 | RE | 10 |
| 27 (re) |  | The Boys Are Back (2010) | £2,476 | £2,476 | £131,892 | RE | 5 |
| 28 (re) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £2,143 | £2,143 | £7,074,379 | RE | 10 |
| 29 (re) |  | Glorious 39 (2009) | £1,528 | £1,528 | £309,071 | RE | 13 |
| 30 (new) | | She, a Chinese (2009) | £1,350 | £1,350 | £1,350 | new | 1 |
| 31 (re) |  | Nowhere Boy (2009) | £1,098 | £1,098 | £1,282,891 | RE | 9 |
| 32 (new) | | Freestyle (2010) | £922 | £922 | £922 | new | 1 |
| 33 (re) | | Mugabe and the White African (2010) | £743 | £743 | £60,153 | RE | 7 |
| 34 (re) |  | The Unloved (2009) | £290 | £290 | £1,304 | RE | 1 |
| 35 (re) |  | 44 Inch Chest (2010) | £53 | £53 | £400,108 | RE | 6 |