| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Clash of the Titans (2010) | £5,682,875 | £5,682,875 | £5,682,875 | new | 1 |
| 2 (new) |  | How to Train Your Dragon (2010) | £4,846,532 | £4,846,532 | £4,846,532 | new | 1 |
| 3 (new) |  | Kick-Ass (2010) | £3,881,704 | £3,881,704 | £3,881,704 | new | 1 |
| 4 (1) |  | Nanny Mcphee and the Big Bang (2010) | £2,600,678 | £4,565,208 | £7,151,968 | 1% | 2 |
| 5 (2) |  | Alice In Wonderland (2010) | £1,285,889 | £3,122,343 | £37,940,131 | -48% | 5 |
| 6 (3) |  | The Blind Side (2010) | £1,003,855 | £2,089,972 | £3,403,289 | -24% | 2 |
| 7 (new) |  | Remember Me (2010) | £987,310 | £987,310 | £987,310 | new | 1 |
| 8 (4) |  | Shutter Island (2010) | £705,499 | £1,482,755 | £9,160,010 | -38% | 4 |
| 9 (5) |  | The Bounty Hunter (2010) | £510,237 | £1,234,552 | £5,144,207 | -49% | 3 |
| 10 (7) |  | The Spy Next Door (2010) | £256,892 | £540,190 | £1,775,684 | -35% | 3 |
| 11 (6) |  | Green Zone (2010) | £170,503 | £478,085 | £5,429,903 | -63% | 4 |
| 12 (11) |  | The Girl With the Dragon Tattoo (2010) | £117,726 | £251,892 | £1,540,009 | -28% | 4 |
| 13 (8) |  | I Love You Phillip Morris (2010) | £112,738 | £391,567 | £2,298,494 | -69% | 3 |
| 14 (10) |  | Avatar (2009) | £107,629 | £301,116 | £91,354,118 | -52% | 16 |
| 15 (re) |  | Shank (2009) | £68,888 | £68,888 | £469,213 | RE | 2 |