| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Fast and Furious 9 (2021) | £6,014,132 | £6,014,132 | £6,014,132 | new | 1 |
| 2 (2) |  | Peter Rabbit 2: The Runaway (2021) | £831,981 | £1,064,615 | £16,352,734 | -25% | 6 |
| 3 (3) |  | In the Heights (2021) | £689,041 | £1,311,669 | £2,385,356 | -36% | 2 |
| 4 (4) |  | A Quiet Place: Part II (2021) | £595,834 | £1,228,672 | £9,568,499 | -42% | 4 |
| 5 (5) |  | Cruella (2021) | £463,369 | £779,906 | £7,803,916 | -37% | 5 |
| 6 (1) |  | The Hitman's Wife's Bodyguard (2021) | £446,546 | £968,234 | £2,604,362 | -73% | 2 |
| 7 (6) |  | The Conjuring: The Devil Made Me Do It (2021) | £298,174 | £655,653 | £8,382,304 | -40% | 5 |
| 8 (new) |  | Supernova (2020) | £245,715 | £245,715 | £245,715 | new | 1 |
| 9 (new) |  | Dogtanian and the Three Muskehounds (2021) | £212,334 | £212,334 | £212,334 | new | 1 |
| 10 (7) |  | The Father (2021) | £134,499 | £441,911 | £1,597,464 | -60% | 3 |
| 11 (8) |  | Nobody (2021) | £56,446 | £187,571 | £1,206,448 | -72% | 3 |
| 12 (12) |  | Tom & Jerry: The Movie (2021) | £36,072 | £44,430 | £889,956 | -43% | 6 |
| 13 (11) |  | Raya and the Last Dragon (2021) | £27,362 | £23,972 | £711,088 | -62% | 6 |
| 14 (10) |  | Godzilla Vs. Kong (2021) | £24,079 | £50,570 | £2,599,827 | -68% | 6 |
| 15 (9) |  | Monster Hunter (2020) | £21,257 | £84,955 | £235,032 | -86% | 2 |