UK Box Office 7th January, 2022
| Title | Weekend | Week | Total | % Change | Total Weeks | ||
| 1 (1) |  | Spider-Man: No Way Home (2021) | £4,477,415 | £9,471,251 | £79,321,181 | -26% | 4 |
| 2 (2) |  | The King's Man (2021) | £905,092 | £1,883,785 | £5,380,412 | -74% | 2 |
| 3 (new) |  | Licorice Pizza (2021) | £879,373 | £879,373 | £879,373 | new | 1 |
| 4 (3) |  | Clifford the Big Red Dog (2021) | £623,074 | £1,384,691 | £7,367,194 | -20% | 5 |
| 5 (4) |  | The Matrix Resurrections (2021) | £513,474 | £1,154,889 | £6,449,812 | -32% | 3 |
| 6 (5) |  | West Side Story (2021) | £404,833 | £853,505 | £5,941,232 | 2% | 5 |
| 7 (new) |  | The 355 (2022) | £366,546 | £366,546 | £366,546 | new | 1 |
| 8 (7) |  | House of Gucci (2021) | £214,743 | £368,791 | £9,122,669 | 35% | 7 |
| 9 (6) |  | Encanto (2021) | £213,516 | £432,055 | £6,600,146 | -12% | 7 |
| 10 (8) |  | Ghostbusters: Afterlife (2021) | £117,398 | £236,222 | £11,289,808 | -8% | 8 |
| 11 (new) |  | Boiling Point (2021) | £79,117 | £79,117 | £79,117 | new | 1 |
| 12 (11) |  | The Electrical Life of Louis Wain (2021) | £66,881 | £172,084 | £257,847 | -22% | 2 |
| 13 (10) |  | '83 (2021) | £34,239 | £75,379 | £526,321 | -60% | 3 |
| 14 (9) |  | Titane (2021) | £29,269 | £74,251 | £196,171 | -76% | 2 |
| 15 (14) |  | No Time To Die (2021) | £26,778 | £39,169 | £96,594,314 | 45% | 15 |
| 16 (new) |  | The 400 Blows (1959) 4K Restoration | £13,620 | £13,620 | £13,620 | RE | 1 |
| 17 (17) |  | The Gruffalos Child w/ Stick Man (2021) | £10,582 | £18,432 | £41,145 | 19% | 6 |
| 18 (25) |  | Ron's Gone Wrong (2021) | £9,946 | £14,430 | £4,633,052 | 80% | 13 |
| 19 (new) | Ailey (2021) | £6,971 | £6,971 | £6,971 | new | 1 | |
| 20 (16) |  | Antarctica (2020) | £6,432 | £15,662 | £411,241 | -32% | 20 |
| 21 (new) | Kesisme Iyi Ki Varsin Eren (2022) | £5,897 | £5,897 | £5,897 | new | 1 | |
| 22 (re) |  | Anything Goes: The Musical (2021) | £4,359 | £4,359 | £774,510 | RE | 5 |
| 23 (19) |  | The French Dispatch of the Liberty, Kansas Evening Sun (2021) | £2,960 | £6,733 | £4,140,038 | -33% | 12 |
| 24 (new) |  | Mission Extreme (2021) | £2,929 | £2,929 | £2,929 | new | 1 |
| 25 (21) | Boxing Day (2021) | £2,881 | £6,016 | £646,598 | 2% | 6 | |
| 26 (new) | Minyan (2022) | £1,773 | £1,773 | £1,773 | new | 1 | |
| 27 (re) | The Rescue (2021) | £1,130 | £1,130 | £86,134 | RE | 5 | |
| 28 (re) |  | The Colour Room (2021) | £914 | £914 | £19,278 | RE | 3 |
| 29 (re) | The Man Who Fell to Earth (1987) Rerelease | £903 | £903 | £62,856 | RE | 1 | |
| 30 (re) |  | Labyrinth (1986) Rerelease | £833 | £833 | £4,570 | RE | 12 |
| 31 (32) |  | Mothering Sunday (2021) | £800 | £1,976 | £497,390 | 57% | 8 |
| 32 (new) |  | Schemes In Antiques (2021) | £678 | £678 | £678 | new | 1 |
| 33 (33) |  | Last Night In Soho (2021) | £495 | £2,494 | £2,331,375 | 52% | 10 |
| 34 (re) |  | Cliff Richard: The Great 80 Tour (2021) | £456 | £456 | £579,590 | RE | 5 |
| 35 (20) |  | A Boy Called Christmas (2021) | £435 | £5,406 | £830,970 | -90% | 7 |
| 36 (39) |  | Eternals (2021) | £430 | £730 | £14,870,100 | 82% | 10 |
| 37 (29) |  | Spencer (2021) | £341 | £3,179 | £2,825,527 | -67% | 9 |
| 38 (re) |  | Shepherd (2021) | £319 | £319 | £24,829 | RE | 2 |
| 39 (re) |  | Tom & Jerry: The Movie (2021) | £292 | £292 | £1,291,600 | RE | 26 |
| 40 (re) |  | The Courier (2020) | £243 | £243 | £2,018,061 | RE | 13 |
| 41 (26) |  | Harry Potter and the Philosopher's Stone (2001) 20th Anniversary | £194 | £1,415 | £1,324,958 | -89% | 43 |
| 42 (23) |  | Paddington (2014) Rerelease 2021 | £148 | £1,181 | £19,582 | -93% | 52 |
| 43 (re) |  | The Last Bus (2021) | £130 | £130 | £466,018 | RE | 11 |
| 44 (35) |  | Censor (2021) | £114 | £114 | £169,264 | -40% | 7 |
| 45 (re) | Men Who Sing (2021) | £105 | £105 | £9,099 | RE | 2 | |
| 46 (37) | Rebel Dykes (2021) | £92 | £277 | £34,304 | -33% | 4 | |
| 47 (re) |  | Cruella (2021) | £13 | £13 | £9,491,691 | RE | 18 |
| 48 (re) |  | The Story of Looking (2021) | £8 | £8 | £7,663 | RE | 2 |