| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Spider-Man: No Way Home (2021) | £3,215,166 | £4,806,587 | £84,127,768 | -28% | 5 |
| 2 (new) |  | Scream (2022) | £2,468,510 | £2,468,510 | £2,468,510 | new | 1 |
| 3 (2) |  | The King's Man (2021) | £627,445 | £1,079,070 | £6,459,482 | -31% | 3 |
| 4 (4) |  | Clifford the Big Red Dog (2021) | £525,107 | £610,724 | £7,977,918 | -16% | 6 |
| 5 (3) |  | Licorice Pizza (2021) | £393,988 | £648,424 | £1,527,797 | -55% | 2 |
| 6 (6) |  | West Side Story (2021) | £350,014 | £659,970 | £6,601,202 | -14% | 6 |
| 7 (5) |  | The Matrix Resurrections (2021) | £299,182 | £545,960 | £6,995,772 | -42% | 4 |
| 8 (9) |  | Encanto (2021) | £221,635 | £240,681 | £6,840,827 | 4% | 8 |
| 9 (8) |  | House of Gucci (2021) | £173,686 | £310,116 | £9,432,785 | -19% | 8 |
| 10 (7) |  | The 355 (2022) | £161,483 | £347,218 | £713,764 | -56% | 2 |
| 11 (10) |  | Ghostbusters: Afterlife (2021) | £90,601 | £125,105 | £11,414,913 | -23% | 9 |
| 12 (11) |  | Boiling Point (2021) | £73,555 | £119,236 | £198,353 | -7% | 2 |
| 13 (re) |  | The Boss Baby 2: Family Business (2021) | £45,993 | £45,993 | £7,278,926 | RE | 10 |
| 14 (new) | | Memoria (2021) | £40,115 | £40,115 | £40,115 | new | 1 |
| 15 (12) |  | The Electrical Life of Louis Wain (2021) | £31,857 | £97,057 | £354,904 | -52% | 3 |