Kamal Haasan
Rangaraja Nambi / Govind Ramasaamy / George W. Bush / Balram Naidu / Avtar Singh / Christian Fletcher / Shinghen Narahasi / Krishnaveni / Vincent Poovaraagan / Kalifullah Khan
Asin Thottumkal
Kothai / Andaal / Radha
Napolean
Kulothunga Chola II
Kantharaj Kasthuri
Medical Doctor
Ken Baranda
Hiro - Japanese Agent
Chris Cavallaro
Lab Technician
Richard Andrew Evans
Undercover Crime Scene Technician
Brian Jennings
Chief of Home Land Security
Nathena Lewis
Lab Technician
Randy Molnar
Race Car Driver
Tony Morales
Lab Technician
Michael Mosher
American Immigration Office
Tom Myers
Crime Scene Technician
Randy Robinson
Lead Detective
David W. Scott
Lab Tech / Detective
Steven Shaver
Lab Technician
Jason Tripp
Ben - Scientist